https://www.orapuh.org/ojs/ojs-3.1.2-4/index.php/orapj/issue/feed 2025-01-14T05:47:47+00:00 Prof. V. E. Adamu [email protected] Open Journal Systems <p>Orapuh Journal (Orap J) is an open-access, internationally peer-reviewed online journal dedicated to oral and public health. The journal provides accessible, high-quality, peer-reviewed knowledge to oral and public health professionals, educators, consumers, and the global community.</p> <p><strong>Aim</strong><br>Orapuh Journal aims to enhance access to superior information and research in oral and public health while fostering the development of emerging researchers and authors, particularly from underserved areas within these disciplines.</p> <p><strong>Scope</strong><br>Orapuh Journal prioritises:</p> <p>1. Original research<br>2. Comprehensive and critical review articles<br>3. Evidence-based information<br>4. Interactive clinical and related content<br>5. Content contributions focused on advancing oral and public health disciplines.</p> <p><strong>Open Access Information</strong></p> <p>All articles in Orap J are open-access articles distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License.</p> <p>Click <a href="https://www.orapuh.org/ojs/ojs-3.1.2-4/index.php/orapj/about"><strong>here</strong></a> to read more about the Journal. Find out <a href="http://orapuh.org/ojs/ojs-3.1.2-4/index.php/orapj/why-choose">why <em>Orap J</em> is your quick access to being</a>!</p> <p><strong><a href="https://orapuh.org/2023/11/01/the-vital-role-of-communicating-dental-and-public-health-research-findings/">Click here</a></strong>&nbsp;to read an article about the vital role of communicating oral and public health research findings to the scientific community.</p> <p><a href="http://orapuh.org/ojs/ojs-3.1.2-4/index.php/orapj/editorial-policies">Editorial Policies</a>&nbsp; &nbsp; &nbsp; &nbsp; <a href="https://orapuh.org/ojs/ojs-3.1.2-4/index.php/orapj/about/editorialTeam">Editorial Team</a>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; <a href="http://orapuh.org/ojs/ojs-3.1.2-4/index.php/orapj/about/submissions">Author Guidelines</a></p> https://www.orapuh.org/ojs/ojs-3.1.2-4/index.php/orapj/article/view/e1201 2025-01-14T05:47:47+00:00 Anderson M. Munenge [email protected] Henry-Jacques M. Bomoi [email protected] Fiston B. Masikini [email protected] Becker T. Kanku [email protected] Prescillia P. Mabubu [email protected] Dénise W. Okito [email protected] Jean-Jacques D. Amogu [email protected] Odette N. Kabena [email protected] Thierry T. Tangou [email protected]

<p><strong>Introduction</strong></p> <p>Schistosomiasis remains widespread in sub-Saharan Africa, particularly in the Central Congo Province of the Democratic Republic of the Congo (DRC), where it is endemic.</p> <p><strong>Purpose</strong></p> <p>This study aimed to assess the knowledge, attitudes, and practices (KAP) of the rural population of Kimpese regarding the prevention of intestinal schistosomiasis.</p> <p><strong>Methods</strong></p> <p>A random sampling technique was employed, using semi-structured and informal interviews to collect data.</p> <p><strong>Results</strong></p> <p>The findings revealed that while 96% of respondents were aware of schistosomiasis, only 41% had knowledge of or practised preventive measures.</p> <p><strong>Conclusion</strong></p> <p>These findings underscore the need to enhance health education and water sanitation initiatives to address this public health challenge.</p>

2025-01-13T14:00:42+00:00 Copyright (c) 2025 Anderson M. Munenge, Henry-Jacques M. Bomoi, Fiston B. Masikini, Becker T. Kanku, Prescillia P. Mabubu, Dénise W. Okito, Jean-Jacques D. Amogu, Odette N. Kabena, Thierry T. Tangou https://www.orapuh.org/ojs/ojs-3.1.2-4/index.php/orapj/article/view/e1202 2025-01-14T05:47:47+00:00 Timothée Mavanga Mabaya [email protected] Jocelyn Mankulu Kakumba [email protected] Mannix Mayangi Makola [email protected] Adelard Mbenza Puati [email protected] Didi Mana Kialengila [email protected] Jean Mavar Tayey Mbay [email protected] Jérémie Mbinze Kindenge [email protected]

<p><strong>Introduction</strong></p> <p>The quality of medicines and healthcare products is a significant challenge these days, with counterfeiting accounting for at least 10% of all products in circulation worldwide, including in Africa. In the specific case of the Democratic Republic of Congo (DR Congo), which is the second-largest country on the continent and faces serious challenges in frontier control, the country has become a major hub for this scourge. Counterfeit medicines circulating within its territory account for over 20% of the pharmaceutical market.</p> <p><strong>Purpose</strong></p> <p>This research aimed to provide a simple, reliable, and economical method for quality control of drugs and healthcare products in the Congolese pharmaceutical market. This was achieved by developing and validating an ultraviolet-visible (UV-vis) spectrophotometric method for the simultaneous determination of paracetamol and ibuprofen in dosage forms.</p> <p><strong>Methods</strong></p> <p>From stock solutions, 0.65 ml of paracetamol and 0.8 ml of ibuprofen were transferred into volumetric flasks to prepare 10 ml of each solution. These solutions were separately scanned between 200-400 nm to observe the absorption maxima of each compound in UV-vis spectra against the blank (ethanol). Subsequently, individual solutions were prepared to obtain calibration and validation standards for the method validation, using the total error strategy and studying various validation criteria (specificity, precision, accuracy, linearity, robustness). After evaluating all the criteria, the developed and validated method was applied for the qualitative and quantitative analysis of dosage forms containing both paracetamol and ibuprofen.</p> <p><strong>Results</strong></p> <p>When solubilized in ethanol, paracetamol and ibuprofen exhibited absorption maxima at 249 nm and 219 nm, respectively. The method demonstrated strong correlation over the concentration ranges used (2.6–9.1 µg/ml for paracetamol and 3.2–9.6 µg/ml for ibuprofen). The correlation coefficients and regression lines determined at selected wavelengths were: y = 0.0924 x (R² = 0.999) and y = 0.0228x (R² = 0.9996) for paracetamol at 249 nm and 219 nm respectively, and y = 0.0429 x (R² = 0.9993) for ibuprofen at 219 nm. The committed bias and the coefficient of variation in the precision study were within ±2% and less than 2%, respectively. Furthermore, the application of the method to dosage forms produced appropriate active ingredient rates, which ranged between 98% and 102%.</p> <p><strong>Conclusion</strong></p> <p>The developed method showed no interference between the active ingredients and the usual excipients used in tablet manufacturing. The recovery rates obtained in the selectivity and accuracy studies were consistently between 98% and 102%. Active ingredient contents determined by applying the method to pharmaceutical dosage forms ranged between 95% and 105%.</p>

2025-01-13T14:48:12+00:00 Copyright (c) 2025 Timothée Mavanga Mabaya, Jocelyn Mankulu Kakumba, Mannix Mayangi Makola, Adelard Mbenza Puati, Didi Mana Kialengila, Jean Mavar Tayey Mbay, Jérémie Mbinze Kindenge