Abstract
Dentinal hypersensitivity (DHS) is a common and significant dental condition typically characterized by a brief sharp pain in response to exogenous, non-noxious stimuli. This condition negatively affects patients’ quality of life and may disturb their eating, drinking, brushing, and sometimes even breathing. The exact nociceptive mechanisms of DHS have not been elucidated. In this paper, the authors carried out a narrative review and explored the etiopathogenesis, presumed mechanisms, risk factors, and epidemiology of DHS. They provided guidelines and suggestions for its diagnosis and management. The process of writing took place over one month, between August 30, and September 30, 2021. During this period, the authors sought relevant works online using various databases like PubMed, Core, Z-library, and Google scholar. Google and Edge search engines were used to obtain the required literature using keywords like “dentinal hypersensitivity”, “tooth sensitivity”, “cervical sensitivity”, “dentin sensitivity”, “cervical hypersensitivity”, etc. The authors extracted and documented vital information from different original articles and textbooks based on the objectives of this work. Included in this paper were systematic reviews on DHS published in the English Language. Articles that are unrelated to the topic, whose full-text was not available, and articles that were not written in the English Language were excluded. The most important risk factors for DHS seem to be the frequency and methods of tooth brushing. Thus, dental healthcare personnel (especially dental therapists) should intensify their effort in educating patients on oral hygiene and proper tooth brushing techniques. A better understanding of the underlying nociceptive mechanisms of DHS will lead to the development of improved, simple, efficient, permanent, and low-cost management techniques for the treatment of patients experiencing DHS.
References
Abuzinadah, S. H., & Alhaddad, A. J. (2021). A randomized clinical trial of dentin hypersensitivity reduction over one month after a single topical application of comparable materials. Sci Rep 11 (6793). https://doi.org/10.1038/s41598-021-86258-3
Addy, M. (2005). Tooth brushing, tooth wear and dentin hypersensitivity – are they associated? International Dental Journal, 55(1), 261-267.
Addy M. (2002). Dentin hypersensitivity: New perspectives on an old problem. International Dental Journal, 52, 367-375.
Aminoshariae, A., & Kulid, J. (2021). Current concepts of dentinal hypersensitivity. Journal of Endodontics, S0099-2399(21)00516-1. https://doi.org/10.1016/j.joen.2021.07.011
Arua, S. O., Fadare, A. S., & Adamu, V. E. (2021). The etiology and management of dentinal hypersensitivity. Orapuh Journal, 2(2), e815.
Bandeca, M. C., Kuga, M. C., Lima, S. L., Escalante-Otárola, W., Castro-Núñez, G., & Jordão-Basso, K. (2017). Treatment protocol for dentin hypersensitivity. World Journal of Dentistry, 8(1), 1- 4.
Bartlett, D. (2011). Tooth wear: Sensitivity. In D. Ricketts, & D. Bartlett, (Eds.), Advanced Operative Dentistry: A Practical Approach. (1st ed., pp. 45-54). Elsevier.
Bekes, K., & Hirsch, C. (2013). Influence of dentin hypersensitivity on oral health related quality of life. Clinical Oral Investigations, 17(1), 45-51.
Borges, A. B., Barcellos, D. C., Torres, C. R. G., Borges, A. L. S., Marcilio, A. L. & Carvalho, C. A. T. (2012). Dentin hypersensitivity- Etiology, treatment modalities and other related factors: A literature Review. World Journal of Dentistry,3(1), 60-67.
Brännström, M. (1996). Reducing the risk of sensitivity and pulpal complications after the placement of crowns and fixed partial dentures. Quintessence Int. 27(10), 673-678.
Brännström, M., & Aström, A. (1972). The hydrodynamics of dentin, its possible relationship to dentinal pain. International Dental Journal, 22(2), 219-227.
Borges, A., Barcellos, D., & Gomes, C. (2012). Dentin hypersensitivity- Etiology, treatment possibilities and other related factors: A literature review. World Journal of Dentistry, 3(1), 60-67.
Bubteina, N., & Garoushi, S. (2015). Dentin Hypersensitivity: A review. Dentistry 5(9), 330-336. https://doi.org/:10.4172/2161-1122.1000330
Canadian Advisory Board on Dentin Hypersensitivity. (2003). Consensus-based recommendations for the diagnosis and management of dentin hypersensitivity. Journal of Canadian Dental Association, 69(4),221–226.
Chu, C. H., & Lo, E. C. M. (2010). Dentin hypersensitivity: a review. Hong Kong Dental Journal 7(1), 15-22.
Cummins, D. (2010). Recent advances in dentin hypersensitivity: clinically proven treatments for instant and lasting sensitivity relief. American Journal of Dentistry, No A:3A – 13A. PMID: 21284246.
Cummins, D. (2009). Dentin hypersensitivity: From diagnosis to a breakthrough therapy for everyday sensitivity relief. Journal of Clinical Dentistry, 20, 1-9.
Davari, A. R., Ataei, E., & Assarzadeh H. (2013). Dentin hypersensitivity: Etiology, diagnosis and treatment; a literature review. Journal of Shiraz University Medical Sciences, 14(3), 136-145.
Femiano, F., Femiano, R., Femiano, L., Nucci, L., Minervini, G., Antonelli, A., Bennardo, F., Barone, S., Scotti, N., Sorice, V., & Sorice, R. (2021). A new combined protocol to treat the dentin hypersensitivity associated with non-carious cervical lesions: a randomized controlled trial. Applied. Sci. 2021, 11, 187. https://dx.doi.org/10.3390/app 11010187
Gbadebo, S. O., Lawal, F. B., & Arowojolu, M. O. (2016). Dentinal hypersensitivity: real or
imagined. Nigerian Journal of Medicine, 25(2), 182 – 188.
Gilliam, D. (2021). The impact of dentin hypersensitivity on quality of life: an overview. Clinical Oral Science and Dentistry, 4(1), 1-6. https://qmro.qmul.ac.uk/xmlui/handle/123456789/71041
Gillam, D., Chesters, R., Attrill, D., Brunton, P. S. M., Strand, P., Whelton, H. & Bartlett, D. (2013). Dentin hypersensitivity - Guidelines for the management of a common oral health problem. Dental update. 40(7), 514-518. https://doi.org/10.12968/2013.40.7.514
Goh, V., Corbet, E. F., Leung, W. K. (2016). Impact of dentin hypersensitivity on oral health-related quality of life in individuals receiving supportive periodontal care. Journal of Clinical Periodontology, 43(7), 595–602.
Grippo, J. O., Simring, M., & Schreiner, S. (2004). Attrition, abrasion, corrosion and abfraction revisited: a new perspective on tooth surface lesions. Journal of American Dental Association, 35(8), 1109–1118.
Gysi, A. (1900). An attempt to explain the sensitiveness of dentin. British Journal of Dental Science, 43(1), 865–868.
Hewlett, E. R. (2007). Etiology and management of whitening-induced tooth hypersensitivity. Canadian Dental Association Journal, 35(7), 499-506.
Jaeggi, T., & Lussi, A. (2006). Prevalence, incidence and distribution of erosion. In A. Lussi, (Ed.), Dental erosion: From diagnosis to therapy. Monographs in Oral Science, 20(1), (pp. 44-65). Basel, Karger, https://doi.org/10.1159/000093362
Jorgensen, M. G., & Carroll, W. B. (2002). Incidence of tooth sensitivity after home whitening treatment. Journal of the American Dental Association, 133(1), 1076-1082.
Kanehira, M., Ishihata, H., & Saito, M. (2015). Dentin hypersensitivity: etiology, prevalence and treatment modalities. In K. Sasaki, O. Suzuki, & N. Takahashi, (Eds.), Interface Oral Health Science, 2014, (pp. 322-325). Springer, Tokyo. https://doi.org/10.1007/978-4-431-55192-8_28
Kim, S. J. (2016). A novel method for the treatment of dentinal hypersensitivity: penetration of magnetic nanoparticles into dentinal tubules. University of Maryland Baltimore Digital Archive. http://hdl.handle.net/10713/5804.
Lima, T. C., Vieira-Barbosa, N. M., Grasielle de Sa Azevedo C., de Matos F. R., Douglas de Oliveira D. W., de Oliveira E. S., (2017). Oral health-related quality of life before and after treatment of dentin hypersensitivity with cyanoacrylate and laser. Journal of Periodontology, 88(2), 166–172
Liu, X. X., Tenenbaum, H. C., Wilder, R. S., Quock, R., Hewlett, E. R., & Ren, Y.-F. (2020). Pathogenesis, diagnosis and management of dentin hypersensitivity: an evidence-based overview for dental practitioners. BioMed Central Oral Health 20(1), 220-229. https://doi.org/10.1186/s12903-020-01199-z
Luukko, K., Kettunen, P., Fristad, I., & Berggreen, E. (2011). Structure and functions of the dentin-pulp complex. In: S. Cohen, & Hargreaves, K. M. (Eds.), Pathways of the pulp. (10th ed., pp. 452-503) Mosby.
Mantzourani, M., & Sharma, D. (2013). Dentin sensitivity: past, present and future. Journal of Dentistry, 41(4), S3-17. https://doi.org/10.1016/S0300-5712(13)70002-2
Marto, C. M., Baptista, P. A., Nunes, T., Pimenta, M., Abrantes, A. M., Pires, A. S., Laranjo, M., Coelho, A., Donato, H., Botelho, M. F., Ferreira, M. M., & Carrilhi, E. (2019). Evaluation of the efficacy of dentin hypersensitivity treatments—A systematic review and follow-up analysis. Journal of Oral Rehabilitation. 46(10), 952–990. https://doi.org/10.1111/joor.12842
Mafla, A. C., & Lopez Moncayo, L. F. (2016). Dentin sensitivity risk factors: A case–control study. European Journal of Dentistry, 10(1), 1-6. https://doi.org/10.4103/1305-7456.175678
Matthews, B., & Vongsavan, N. (1994). Interactions between neural and hydrodynamic mechanisms in dentin and pulp. Archives of Oral Biology, 39(1), 87S.
Mendes, S. T. C., Pereira, C. S., Leite de Oliveira, J., Santos, V. C. S., Gonçalves, B. B., & Mendes, D. C. (2021). Treatment of dentin hypersensitivity with laser: systematic review. Brazilian Journal of Pain, 4(2), 152-160.
Orchardson, R., & Collins, W. J. (1987). Clinical features of hypersensitive teeth. British Dental Journal, 162(7), 253-256.
Ozen, T. & Orhan, K. (2009). Dentin hypersensitivity: A randomized clinical comparison of three different agents in a short-term treatment period. Operative Dentistry, 34(4), 392-398.
Pashley, D. H. (1996). Dynamics of the pulpodentin complex. Critical Review of Oral Biology and Medicine, 7(1), 104.
Peeran, S. W., & Ramalingam, K. (2021). Essentials of periodontics & oral implantology. Saranraj JPS Publication
Prabhu, A., Nalawade K., & Balasubramanian, K. (2017). Dentin Hypersensitivity: a review. International Journal of Scientific Research. 6(7). 292.
Rapp, R., Avery, J. K., & Strachan, D. S. (1967). The distribution of nerves in human primary teeth. The Anatomical Record, 159(1), 89 103. https://doi.org/:10.1002/ar.1091590113
Reshma, A. S., Masthan, K. M. K., Babu, A., N., & Anitha, N. (2020). Dentinal hypersensitivity. European Journal of Molecular & Clinical Medicine, 7(3), 1752-1760.
Savage, K. O., Oderinu, O. H., Oginni, A. O., Uti, O. G., Adegbulugbe, I. C., & Dosumu,O. O. (2019). Dentin hypersensitivity and associated factors: a Nigerian cross-sectional study. Pan African Medical Journal, 33(1), 272-283. https://doi.org/10.11604/pamj.2019.33.272.18056
Soares, A., Chalub, L. L., Barbosa, R. S., Campos D. C., Moreira, A. N., & Ferreira, R. C. (2021).
Prevalence and severity of non-carious cervical lesions and dentin hypersensitivity: association with oral health-related quality of life among Brazilian adults. Heliyon, 7(3), e06492. https://doi.org/10.1016/j.heliyon.2021.e06492
Tusharluthra, Gupta, S., Bharadwaj, S., Choubey, A., Yadav, H., Singh, H. (2015). Dentin hypersensitivity and its management: a review. IJOCR, 3(3), 59-63.
Vijay, M., Rahul, M., Neeraj, A., & Savita, G. (2011). Dentin hypersensitivity: recent concepts in management. Journal of Indian Academy of Oral Medicine and Radiology, 23, 115-119. https://doi.org/10.5005/jp-journals-10011-1108
West, N. X. (2006). Dentin hypersensitivity. In A. Lussi, (Ed.), Dental erosion: From diagnosis to therapy. Monographs in Oral Science, 20(1), (pp. 173-189). Basel, Karger, https://doi.org/10.1159/000093362
West, N. X., Lussi, A., Seong, J., & Hellwig, E. (2013). Dentin hypersensitivity: pain mechanisms and etiology of exposed cervical dentin. Clinical Oral Investigation, 17(1), S9–19.
West, N. X., Sanz, M., Lussi, A., Bartlett, D., Bouchard, P., & Bourgeois., D. (2013) Prevalence of dentin hypersensitivity and study of associated factors: A European population-based cross-sectional study. Journal of Dentistry, 41(10), 841-851.
Zeola, L., Soares, P., & Cunha-Cruz, J. (2019). Prevalence of dentin hypersensitivity: systematic review and meta-analysis. Journal of Dentistry, 81, 1–6. https://doi.org/10.1016/j.dent.2018.12.015
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